International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]

VOLUME 25(19) (2024)

Associations of Host Characteristics, Immunisation History and Rash Onset with Measles-Rubella Specific Immunoglobulin M (IgM) Status in South Sulawesi

Basri¹, Ansariadi², Andi Zulkifli Abdullah³ , A. Asrunan Arsin⁴ , Lalu Muhammad Saleh⁵ , Asnawati Amqam⁶ , Indra Dwinata⁷

¹FETP Student, Hasanuddin University, Indonesia.

^2,7 FETP, Faculty of Public Health, Hasanuddin University, Indonesia.

^3,4,5,6 Lecturer of Faculty of Public Health, Hasanuddin University, Indonesia.

Abstract

Measles and rubella are viral diseases that are transmitted through the air by droplets, and are one of the most common and highly contagious diseases. Measles and rubella infections have similar symptoms when viewed from the symptoms that appear in patients where fever and maculopapular rash as the main symptoms. The aim of the study was to determine the relationship of host characteristics, measles-rubella immunisation history and specimen collection time to immunoglobulin M (IgM) infection markers in suspected measles-rubella patients in South Sulawesi Province. Observational research with a Cross Sectional Study design using secondary data from the Case Based Measles Surveillance (CBMS) programme of the South Sulawesi Provincial Health Office in 2019-2023 (June). A total of 675 suspected measles-rubella cases had specimens collected for IgM confirmation. The results were 25.2% (n = 170/675) positive and 74.8% (n = 505/675) negative. In terms of gender, there was no significant difference between males (23.1%; n = 78/337) and females (27.2%; n = 92/338) who were IgM positive. As for the age group variable, the highest positive IgM was in the age group of 2-5 years, 35.6% (n = 48/135) and the lowest in the age group of >30 years, only 5.6% (n = 3/54). Measles-rubella IgM positive immunised 60.4% (n = 408/675), never/unknown immunisation status 39.6% (n = 267/675). Sampling time variable 0-3 days was 56.0% (n = 378/675) and 4-28 days was 44.0% (n = 297/675). The results of this study reported positive measles-rubella IgM serological test results were not associated with age, gender and time of specimen collection. However, statistically (p value = 0.000) there was an association between MR immunisation status and positive measles-rubella IgM status in South Sulawesi in 2019-June 2023.

Keywords: measles, rubella, CBMS, specimen collection time

Full length article – PDF   *Corresponding Author, e-mail: ibaskaminah@gmail.com            Doi # https://doi.org/10.62877/49-IJCBS-24-25-19-49