International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]
VOLUME 25(19) (2024)
Healing of large periapical lesion by Regenerative Endodontic procedure in immature and mature permanent teeth with/without collagen-hydroxyapatite scaffold: A Case report
Menna Allah Ali Abdeldaiem Ali, Maram Farouk Obeid, Abeer Abdelhakim El Gendy
Endodontic department, Ain Shams University , Egypt
Abstract
The purpose of this case report is to report healing of a large periapical lesion with average size of the lesion 9.538 cm3 related to immature and mature necrotic teeth using a novel collagen-hydroxyapatite scaffold in regenerative endodontic procedure. Apical periodontitis related to tooth number seven and eight with (in the same patient) was determined from preoperative cone beam computed tomography scans. Teeth were treated via a revascularization protocol using 1.5% sodium hypochlorite irrigant, a double antibiotic paste was placed for 21 days, collagen-hydroxyapatite scaffold and a coronal seal of mineral trioxide aggregate, and glass ionomer restoration were placed in the second visit. After 1-year follow-up, teeth showed resolution of clinical signs and symptoms in addition to resolution of periapical radiolucency. Results from this case show that regenerative endodontic procedure is an effective treatment option for both immature and mature teeth with apical periodontitis. Based on this case report, the following recommendations are made to help with the regenerative endodontic technique: (1) patient compliance for multiple appointment treatment plan may be significant for case selection. (2) Optimum disinfection protocol is a key factor for success of regenerative endodontic process. (3) Preserving coronal seal throughout interappointment time and after completion of treatment.
Keywords: Immature, scaffold, hydroxyapatite, mineral trioxide aggregate, regeneration
Full length article – PDF *Corresponding Author, e-mail: menna.ali1991@gmail.com Doi # https://doi.org/10.62877/87-IJCBS-24-25-19-87