International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]

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VOLUME 26(20) (2024)

Autologous Transplantation of Dental Pulp Tissue – a Radiographic Evaluation

Dina Nashaat Hassan Hussein*a, Ehab El Sayed Hassanien b, Ashraf Abu Seida c, Tarek Mostafa Abdel Aziz d

*a Endodontic Department, Ain Shams University, Cairo, Egypt

b Professor of Endodontics, Galala University, Suez, Egypt

c Professor of Surgery, Anesthesiology & Radiology, Faculty of Veterinary Medicine,  Cairo, Egypt

d Associate Professor of Endodontics, Ain Shams University, Cairo, Egypt

Abstract

   The study used decellularized autologous pulp tissue as a scaffold for regeneration of root canals of immature infected teeth. Four dogs’ premolar teeth were used. 96 roots of premolars were divided into four groups according to the treatment protocol. Group I: Dental pulp tissue transplantation and blood clot. Group II: Dental pulp tissue transplantation. Group III: Conventional regeneration. Group IV: Negative control group. Each subgroup was radiographically evaluated. Results revealed that after one as well as three months, there was no statistically significant difference between percentage increase in root lengths in the four groups, while in all groups, the percentage increase in root length after three months showed statistically significantly higher value than one month (P-value <0.001). Regarding dentin thickness, after one as well as three months, there was no statistically significant difference between percentage increase in dentin thickness in the four groups, while in all groups, the percentage increase in dentin thickness after three months showed statistically significantly higher value than one month (P-value <0.001). After one as well as three months, there was a statistically significant difference between percentages of apical closure in the four groups. Pair-wise comparisons between groups revealed that Group IV showed the statistically significantly highest percentage of apical closure. In all groups, the percentage of apical closure after three months showed statistically significantly higher value than one month (P-value <0.001). Decellularized pulp tissue can be successfully used as a scaffold in promoting pulp tissue regeneration.

 

Keywords: Dental Pulp, Decellularization, Regeneration

 

Full length article    *Corresponding Author, e-mail: dinanhuss@gmail.com                https://doi.org/10.62877/26-IJCBS-24-26-20-26

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