International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]

VOLUME 25(19) (2024)

Evaluation of Vitamin D Levels in Obsessive‑Compulsive Disorder

Amal Zakaria Ahmed*

Lecturer of psychiatry, Suez Canal University , Egypt

Abstract

Vitamin D has a crucial part in calcium metabolism & has been recognized for its involvement in processes including proliferation, differentiation, and immunomodulation. Recent research has indicated that a lack of vitamin D might cause detrimental alterations in the brain & may be linked to neuropsychiatric disorders. To determine the association among low vitamin D levels & the presence of OCD, & to assess the relationship among low vitamin D levels & OCD symptoms severity & the duration of the illness. Thirty OCD patients and thirty matched healthy controls was enrolled in the research. Information was gathered from individuals diagnosed with OCD who were between the ages of eighteen and forty. The participants’ vitamin D blood levels were evaluated utilizing an enzyme-linked immunosorbent test kit in the present investigation. This study demonstrates a considerable disparity in vitamin D3 levels between the patients and controls. Moreover, The prevalence of deficiency was greater among patients than controls, although the disparity was not statistically significant. We noted that there is a significant negative relationship among vitamin D3 with obsession & compulsion. We can therefore conclude that OCD is related with a deficiency in levels of vitamin D in the serum. Moreover, according to the current findings, there is no correlation among serum vitamin D levels, OCD symptoms, or severity.

Keywords: vitamin D,  severity, Obsessive‑Compulsive Disorder (OCD).

Full length article – PDF   *Corresponding Author, e-mail: amalzakria8102014@gmail.com                  Doi # https://doi.org/10.62877/29-IJCBS-24-25-19-29