International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]
VOLUME 27(21) (2025)
Effect of Gamma Radiation on Adaptability of Mineral Trioxide Aggregate (MTA) and Nano Mineral Trioxide Aggregate (Nano-MTA) as Root-End Filling Materials (An In vitro study)
Fatma Y. Abd-ElHamid1″*”, Tariq Yehia Abdelrahman2, Eman M. F. El-Maghraby1, Abeer A. El Gendy2
1*Health Radiation Research Depart., National Center for Radiation Research & Technology, Atomic Energy Authority, Cairo, Egypt
2Endodontics Dept., Faculty of Dentistry, Ain Shams University, Cairo, Egypt
Abstract
This study aimed to assess and compare the effect of gamma irradiation on the marginal adaptability of mineral trioxide aggregate (MTA) and Nano-MTA to root-end cavity walls using scanning electron microscopy (SEM). Twenty-eight extracted human single-rooted teeth were divided into two groups (n=14 each): Non-irradiated, irradiated group, then each group was subdivided according to the material used MTA and Nano-MTA. Irradiated groups were exposed to a fractionated dose of 60 Gy to simulate clinical radiotherapy. Root-end resections and standardized retrograde cavity preparations were performed, followed by root-end filling with either MTA or Nano-MTA. Samples were stored in physiologic saline at 37°C. Transverse sections were prepared and examined using scanning electron microscope. Data were statistically analyzed using ANOVA and Tukey’s post-hoc tests. Irradiated samples showed wider marginal gaps than non-irradiated groups with no statistically significant difference. Among all groups, Nano-MTA exhibited superior marginal adaptation with less size of gaps than conventional MTA, particularly in the non-irradiated group. Nano-MTA showed better marginal adaptation over conventional MTA, even after exposure to gamma irradiation suggesting its potential as a more effective root-end filling material.
Keywords: Radiotherapy, Marginal adaptation, MTA, Nano-MTA, Scanning electron microscope.
Full length article *Corresponding Author, e-mail: fatma.yehia1111@gmail.com, Doi # https://doi.org/10.62877/37-IJCBS-25-27-21-37