International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]
VOLUME 25(19) (2024)
Analysis of the Combination of Sago Grub Flour (Rhynchophorus ferrugineus) and Moringa Leaf Flour (Moringa oliefera L.) in Increasing Hemoglobin Levels in Mice
Lisnawaty1*, Syefira Salsabila1, Theodora Regina Stephanie Rere1, Yusuf Sabil2, Sartiah Yusran2
1Department of Nutrition, Faculty of Public Health, Halu Oleo University, Kendari, Indonesia
21Department of Public Health, Faculty of Public Health, Halu Oleo University, Kendari, Indonesia
Abstract
Anemia is a global health problem that contributes to increased morbidity and mortality, decreased work productivity, and impaired neurological development. The most common type of anemia is iron deficiency anemia. Traditional/local foods can be utilized to address the problem of anemia. Food ingredients that can be used as natural ingredients to overcome anemia include sago grubs and moringa leaves. Sago grubs (Rhynchophorus ferrugineus) have a high content of protein, amino acids, iron, and good fats. Moringa leaves (Moringa oliefera L) are known to have nutritional content of iron, protein, vitamin A, vitamin C, potassium, and calcium, which are very important in increasing hemoglobin. This study aims to analyze the effect of giving a combination of sago grub flour and moringa leaf flour on hemoglobin levels in anemic mice. This study used sago grubs as the main ingredient for making sago grub flour, moringa leaf flour, and 30 female BALB/c mice divided into 5 groups: PC, NC, T1 (25% sago grub flour: 75% moringa leaf flour), T2 (50% sago grub flour: 50% moringa leaf flour), and T3 (75% sago grub flour: 25% moringa leaf flour). Statistical analysis was performed using the one-way ANOVA test and the results obtained were p=0.000 (p<0.05), then the Post Hoc test was performed and the results obtained were T1 (p=0.000), T2 (p=0.004), and T3 (p=0.125), which means there is an effect of the combination of sago grub flour and moringa leaf flour on increasing Hb levels in anemic mice. However, of the three treatments, the most influential group was the T3 group, which was able to increase hemoglobin from 6.3 mg/dl to 15.36 mg/dl.
Keywords: Anemia, hemoglobin levels, moringa leaves, sago grubs
Full length article – PDF *Corresponding Author, e-mail: lisnawaty@uho.ac.id Doi # https://doi.org/10.62877/95-IJCBS-24-25-19-95