International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]
VOLUME 25(19) (2024)
Utilization of Broiler Skin Gelatin as Wound Healing Medicine
Trisusanti1, M. I. Said2, and R. Malaka2
1 Postgraduate Student of Animal Science and Technology, Faculty of Animal Science, Hasanuddin University, Indonesia
2 Department of Animal Production, Faculty of Animal Science, Hasanuddin University, Indonesia
Abstract
Gelatin is a protein-derived compound obtained by extracting animal collagen. Gelatin can be extracted from broiler chicken skin and used as a wound therapy drug. This study aims to explain the effect of using chicken skin gelatin on the healing process of cut wounds in animal models of mice. The 25% chicken skin gelatin ointment formulation was homogenized with ointment additives such as 0.2% preservative, 3.7% emulsifier, and 71% moisturizer. Testing the physical quality of spreadability and stickiness of chicken skin gelatin ointment using a T-test. Testing the ability to treat cuts using a Completely Randomised Design with 3 treatments namely P1 = administration of NaCl (negative control), P2 = administration of broiler skin gelatin ointment, and P3 = administration of Commercial ointment (positive control) each repeated 5 times. The test results of spreadability and stickiness of chicken skin gelatin ointment showed different results with commercial ointment. The chicken skin gelatin ointment produced is an ointment with a semisolid texture in the form of semi-stiff (high viscosity). The results of testing the treatment of cut wounds with three different treatments obtained results that were significantly different (P <0.01) on the description of the level of wound healing, the percentage of wound healing, and histopathological observations. From the results of the research conducted, gelatin from broiler chicken skin is effective as a wound therapy drug and the healing process of cut wounds in mice is best in treatment using chicken skin gelatin ointment.
Keywords: Chicken skin, Collagen, Gelatin, Wound therapy drug.
Full length article – PDF *Corresponding Author, e-mail: irfanunhas@gmail.com; irfan.said@unhas.ac.id Doi # https://doi.org/10.62877/37-IJCBS-24-25-19-37