International Journal of Chemical and Biochemical Sciences (ISSN 2226-9614)[/vc_column_text][/vc_column][/vc_row]
VOLUME 25(19) (2024)
Blood cholinesterase enzyme activity profile of fogging officers at the Makassar health quarantine centre
Wahyudi Hidayat1.3*, M. Furqaan Naiem2, Masyitha Muis2
1Student of Department of Occupational Health and Safety, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
2Department of Occupational Health and Safety, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia
3Health Quarantine Centre, Makassar, Indonesia
Abstract
The use of pyrethroid chemicals as insecticidal compounds, which are indicated to be relatively safe for humans, has been shown to contribute to physiological system disruptions upon exposure. Therefore, it is crucial to continue exploring predictors that can affect cholinesterase enzyme activity as a preventive measure against health risks. This study aims to identify the relationship between factors influencing blood cholinesterase enzyme activity in fogging officers at the Makassar Health Quarantine Center. This research is an analytical observational study with a cross-sectional laboratory-based approach involving 31 fogging officers from the Makassar Health Quarantine Center, using correlation tests for statistical analysis. The results indicate that the statistical correlation values are low, showing a weak relationship between pesticide exposure characteristics (such as respondent age, work duration, body mass index, knowledge level, fogging actions, PPE use, insecticide dosage, fogging frequency, exposure duration, and health complaints) and the blood cholinesterase enzyme activity of the officers. However, laboratory reference values revealed abnormal cholinesterase levels in 6.45% of respondents, particularly among males. Additionally, 89.7% of respondents reported health complaints following fogging activities. Although the results do not show a strong or statistically significant correlation between pesticide exposure characteristics and blood cholinesterase enzyme activity in fogging officers, the finding of cholinesterase levels above laboratory reference values is important for further assessing the health conditions of exposed workers and targeting the best preventive evaluations according to occupational health and safety standards.
Keywords: Enzyme, Cholinesterase, Fogging, Pesticide, Pyrethroid
Full length article – PDF *Corresponding Author, e-mail: wyudihidayat.kkpmks1@gmail.com Doi # https://doi.org/10.62877/53-IJCBS-24-25-19-53